What is oxidative stress and free radicals ?

What is oxidative stress and free radicals ?

What is oxidative stress and how to reduce it?

Oxygen (or dioxygen, O2) is a gas essential to life. With the exception of some organisms, oxygen is essential to all animals, plants and bacteria in producing energy.

During evolution, living species adapting to oxygen resulted in the appearance of enzymes to help its consumption. During this process of cellular respiration, the body produces molecules that can be toxic. These molecules are called free radicals.

Free radicals are inevitable as they are produced daily during the body’s metabolism. The phenomenon is observable when an apple left in the open air turns brown, or when iron exposed to air and humidity turns to rust.

oxidative stress process

Oxidative damage due to an excess of free radicals are the major cause of cell senescence and aging. Although their excess must be controlled, their presence is nevertheless essential to stimulate cell repair and homeostasis mechanisms, especially in the defence against bacteria.



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The body’s defence system

The body possesses a defence system to control these free radicals. There is a delicate balance between the production of free radicals and our body’s antioxidant defence system. It is for this reason that the cell can continue to function despite the formation of these free radicals.

The body’s defence system is composed, on the one hand, of antioxidant molecules that come in part from our overall diet. Some include Vitamins A, C and E, but also coenzymes Q10, carotenoids, polyphenols and trace elements such as zinc and selenium. On the other hand, the body has an endogenous enzymatic system with a much greater antioxidant capacity. These antioxidant enzymes contain superoxyde dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), which are essential to neutralize free radicals.

vitamin food

A healthy and balanced diet (vegetables, fruits, fish, soybean oil) should theoretically be sufficient to provide the essential antioxidants and trace elements our body needs to minimize the harmful effects of free radicals as much as possible.



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The body’s defence system

However, in our daily routine we face pollution, extended sun exposure (UV), smoking, alcohol or drug consumption, which all contribute to generating an excessive level of free radicals.

When this production exceeds the body’s antioxidant defence capacities or when the immune system weakens, this imbalance is defined as a state called oxidative stress.

Oxidative stress can contribute to the development of various health issues:
• fatigue;
• joint pain;
• hypertension;
• headaches;
• anxiety;
• diabetes;
• insomnia;
• memory loss...

oxidative stress


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The intake of dietary supplements to fight oxidative stress

Even if we have a healthy lifestyle, we have to face on a daily basis the sun, pollution, stress, viruses and microbes that generate an excess of free radicals leading to oxidative stress.

It is not necessary to consume large quantities of antioxidants, as we risk breaking the equilibrium of the pro/antioxidant balance. For this reason, it is advised to establish rest periods (commonly called “washouts”) of two to three weeks during the intake of vitamin and mineral-based dietary supplements.

GliSODin is a unique compound formed by combining a melon extract, naturally rich in an antioxidant enzyme called superoxide dismutase (SOD), and a protein derived from wheat called gliadin. Included in the formulation of dietary supplements made by Laboratoires Isocell, GliSODin prepares the body to respond effectively to oxidative stress through faster mobilization of endogenous defences in order to permanently maintain the pro/antioxidant balance.

melon glisodin


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Enjoy the anti-aging effects of a dietary supplement against oxidative stress

Free radicals are some of the main contributors to premature aging. Over time, they cause cell damage, and the steady buildup of these damages contributes to accelerating skin aging.

Skin damage caused by free radicals can appear in several forms:
o hyperpigmentation;
o broken blood vessels;
o loss of skin firmness;
o loss of skin elasticity;

The effectiveness of antioxidant defences reduces with age, while free radical levels increase. Skin is our main line of defence, it is necessary to apply creams to protect it. This topical protection can be strengthened internally with the intake of a dietary supplement to help rebuild damaged skin tissue due to a state of oxidative stress.

what is oxidative steess

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